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Delta-8 THC: what the research says

A double-bond isomer of delta-9 THC, present only in traces in the plant; the commercial supply is converted from hemp CBD. Sold here as distillate.

How it interacts with receptors

CB1 partial agonist with lower affinity than delta-9; older human work rated it at roughly two-thirds of delta-9's potency (Hollister & Gillespie 1973).

What human research reports

A 2022 survey of 521 users reported that most described it as similar to delta-9 with milder side effects (Kruger & Kruger 2022). A 1995 Israeli study gave delta-8 to eight children receiving chemotherapy and reported vomiting was prevented (Abrahamov 1995). A 2022 pharmacology review (Tagen & Klumpers) concluded the two isomers are qualitatively similar with delta-8 the gentler of the two.

Animal and cell research

Appetite stimulation in mice at very low doses (Avraham 2004).

Delta-8 THC at Vivimu

• Pineapple Express Delta 8 Distillate
  Was $99.99 Now $35.72 · 28g (1 oz) - or subscribe
• Girl Scout Cookies Delta 8 Distillate
  Was $43.98 Now $18.40 · 7g - or subscribe
• NYC Diesel Delta 8 Distillate
  Was $43.98 Now $18.40 · 7g - or subscribe
• Blueberry Cookies Delta 8 Distillate
  Was $43.98 Now $18.40 · 7g - or subscribe
• Bulk Delta 8 THC Distillate (KCA Compliant)
  $579.99 - or subscribe
• Delta 8 THC Distillate
  Was $24.99 Now $10.81 · 28g (1 oz) - or subscribe
• Flavored Delta 8 Trio — Girl Scout Cookies + Pineapple Express + Blueberry Cookies (3 × 28 g)
  $65.99
• Delta 8 Water Soluble
  Was $179.98 Now $64.96 · 28g (1 oz) - or subscribe

Lab-tested, ships everywhere except Colorado. Want a specific amount? The blend builder does the weighing math and can add the exact sizes to your cart.

Sources

1. Tagen M, Klumpers LE. Review of delta-8-tetrahydrocannabinol: comparative pharmacology with delta-9-THC. Br J Pharmacol 2022;179:3915-33.
2. Kruger DJ, Kruger JS. Delta-8-THC: delta-9-THC's nicer younger sibling? J Cannabis Res 2022;4:4.
3. Abrahamov A, Abrahamov A, Mechoulam R. An efficient new cannabinoid antiemetic in pediatric oncology. Life Sci 1995;56:2097-102.

Published research, summarised for education — not medical advice. Talk to a licensed clinician about your own situation.